Simparica is a fast-acting oral flea and tick preventative that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. What is Simparica? Is a flea and tick preventative that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. It is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (Lone Star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick). What are the benefits of Simparica? Each tablet provides a full month of protection against ticks and fleas Easy to administer Formulated for: Dogs How does this medication work? Simparica contains the active ingredient sarolaner, which inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular junction in insects. This results in uncontrolled neuromuscular activity leading to death in insects or acarines. Simparica is administered once a month directly by mouth or can be crumbled and mixed with food. To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with an approved flea control product. How is this medication given? Give this medication exactly as directed by your veterinarian. What form(s) does Simparica come in? Tablet Common Brand Name: Simparica Generic Name: Sarolaner Dose and Administration: Simparica should be administered orally, once every month. Use according to your veterinarian's instructions. Possible Side Effects: The most frequently reported adverse reactions were vomiting and diarrhea. Simparica may cause abnormal neurologic signs such as tremors, decreased conscious proprioception [awareness of body position and movement], ataxia [loss of full control of bodily movements], decreased or absent menace [blinking reflex], and/or seizures. Precautions: The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. Storage: Store at or below 86°F (30°C) with excursions permitted up to 104°F (40°C). A prescription from your veterinarian is required to Simparica. Size: 5.6-11 lbs.
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